There aren't many actors more highly regarded than Anthony Hopkins, who still manages to impress us at this late stage in his career. Known to many as Hannibal Lecter from The Silence of the Lambs, Hannibal, and Red Dragon, Hopkins had the opportunity to perform in a comics adaptation—but he declined. Before Michael Caine boarded Christopher Nolan's Batman Begins as Bruce Wayne's butler, Alfred Pennyworth, Nolan reportedly offered Hopkins the role. He turned it down, for reasons unknown. Thankfully he did, because without Caine as Alfred, Nolan likely never would have developed the close relationship with Caine that's led to the duo working together repeatedly throughout Nolan's films.
Interestingly, despite reportedly being turned down for the role of Mr. Freeze in Joel Schumacher's Batman & Robin (a role he lost to Arnold Schwarzenegger), Hopkins maintained his interest in DC movies. Not long after turning down the role of Alfred Pennyworth in Batman Begins, he finally joined the DC universe as Jor-El in J.J. Abrams and Brett Ratner's Superman: Flyby. Things didn't work out, though, and the project mutated into Bryan Singer's Superman Returns. "I was going to do the movie with Brett, and I don't know what happened," Hopkins told MTV News. "[There was] some political movement. I think Brett was out of line with something and they said thank you very much. I never heard from Brett since then, but I was all set to do it." Is Hopkins secretly a huge comic book fan, and we just didn't know about it? At least he got his chance to play Odin in Marvel's Thor movies.