Collaborating with Smirnoff's social media coordinators, Cuoco played 21 Questions and dished about her favorite selections from the brand. She revealed her favorite cocktail is one of her own creations called the "Cuocotail," a mix of Smirnoff No. 21 vodka — "obviously," — ginger and jalapeño-infused vermouth, cucumber, and a Tajín-coated rim.