Pompeo's second favorite moment occurred a few episodes later in an installment titled "Deny, Deny, Deny," when Christina’s traumatic pregnancy, her breakup with Burke, and her mother's meddling become too much to bear and she screams the relatable line, "Somebody sedate me!" It's a scene that's just as hilarious as it is heartbreaking; it's no wonder these two moments continue to stand out for Pompeo.