Heath Freeman played Howard Epps, the first of several diabolical serial killers with whom the team tangled throughout the series' network run. After “Bones,” Freeman moved between television and indie features, before his sudden death in November 2021 at the age of 41.

Hassell appeared in Season 6's grisly "The Daredevil in the Mold" as a BMX rider, but was also in feature films like “Southland” and "The Kids Are All Right.” He was murdered outside his girlfriend's apartment during an apparent attempted carjacking at just 30 years old.

Known for his hits with Heavy D & The Boyz, Heavy D was a recurring cast member in Season 1, in addition to being the vice president of A&R for Uptown. Sadly, he passed away from a pulmonary embolism at the age of 44 in 2011.

Holbrook played Red Hudmore, a military veteran up to dark deeds in the episode "New Tricks in the Old Dogs.” Holbrook was Hollywood royalty who garnered an Oscar nom, a Tony win, and five Emmy awards during his five decade career. He died at his home in 2021, at the age of 95.

Thomas played a magician’s club owner in Season 11’s "The Promise in the Palace.” A popular radio DJ, Thomas segued into stand-up comedy and acting with recurring roles on "Murphy Brown" and "Cheers." The 69-year-old actor died of cancer on August 24, 2017.