In previous adventures, Hulk merely appeared to be a mindless beast, but there was actually some aspect of Bruce Banner holding him back. In The Incredible Hulk #300, however, Bruce Banner's mind had committed a kind of abdication, leaving only the Hulk personality in charge. This "Savage" Hulk immediately begins wrecking New York, leading to a fantastic "Hulk vs. everyone" fight. S.H.I.E.L.D. is not able to stop him, nor is Spider-Man. Hulk also fights off Luke Cage, Iron Fist, and Human Torch, and eventually, the Avengers show up.
What follows is a terrific battle, with each Avenger using his or her particular skills to try to subdue Hulk. However, they have the same amount of luck that the other heroes have had, until it's down to just Thor vs. Hulk. They fight across huge swathes of Manhattan, and the battle has some memorable moments, such as Hulk throwing an adamantium statue of himself directly at Thor. Just when it looks like the battle between the two may destroy the entire city, Doctor Strange uses his mystic arts to exile Hulk to another dimension. While this won't be the first time Hulk is forcibly exiled from the Earth, it does go as another victory for him over Thor. Doctor Strange had to magick him to another dimension, for crying out loud!