If you go to a party at a creepy castle, don't wander around, or else you run the risk of being possessed by an ancient space witch. That's just common sense. Unfortunately, June Moone didn't get the memo, nor did she answer the call that told her not to talk to giant lumpy heads she might find behind walls. Now she plays host to a powerful evil that she can only sometimes control, causing her to slip between hero and villain pretty regularly.
When the Enchantress first appeared in 1966, she only showed up in three stories, where she immediately knew how to use every single occult power ever imagined. With demons, there's no learning curve; you just trade your soul for skill. After her first appearances, she was forgotten until 1980. By then, the forces that gave her power had gone rotten, and she attacked Supergirl. (Add sanity to the list of things you give up when you accept Satan's power.) Enchantress has been separated from and reunited with the dark soul that fuels her a few times, leaving her catatonic or tucked safely away in an asylum each time, so she's kinda damned either way, making her a pretty good candidate for the Suicide Squad.